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Goodnight, Sleep tight, don’t take your immunity light!


“Early to bed and early to rise makes one healthy, wealthy and wise.”

Day and night have existed for as long as the earth and sun- since before the beginning of life forms. So, it is not surprising that a large number of organisms, including all eukaryotes, have evolved considering day and night cycles. These changes that happen at physical, mental, behavioral, and molecular levels are referred to as circadian rhythms. Scientists have studied circadian rhythms for decades, and recently, Jeffrey C. Hall, Michael Rosbash, and Michael W. Young, who uncovered major genes responsible for circadian rhythms, were awarded the Nobel Prize. Common examples of the effects of circadian rhythm include body temperature, wakefulness, sleepiness, and hormonal activity.

The central circadian proteins include BMAL1 (Brain and Muscle ARNT-Like 1) and CLOCK (Circadian Locomotor Output Cycles Kaput), which are present in all mammalian cells and help in keeping track of…

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